
Chronic sinus pressure, congestion, and recurring infections can make every day feel harder. Our specialists identify the underlying causes of your symptoms and create a personalized plan to bring lasting relief and clearer breathing.

Chronic sinusitis can significantly disrupt daily life, causing persistent fatigue, congestion, drainage, and headaches. Many people are surprised to learn that chronic sinusitis can impact quality of life even more than major heart failure. If you’re among the millions who struggle with ongoing sinus symptoms, you may feel like you’ve tried everything without real relief. At Modena Allergy & Asthma – Eastlake, we work closely with patients to explore effective and innovative therapies for chronic nasal and sinus conditions.
Several monoclonal antibody therapies have recently been approved for chronic sinusitis, with more under development. In addition to FDA-approved treatments, our team participates in clinical trials evaluating new and promising options. These therapies target the underlying inflammation that drives sinus disease, rather than providing short-lived symptom relief.
If you’re ready to finally get control of your chronic sinusitis, Dr. Brian Modena and the team at Modena Allergy & Asthma – Eastlake are here to help.

Chronic sinusitis, also known as chronic rhinosinusitis (CRS), is characterized by persistent symptoms such as nasal congestion, facial pressure, headache, and postnasal drip that last for at least three months. These issues stem from ongoing inflammation in the sinuses (the air-filled cavities in the skull) and the nasal passages. The impact of CRS extends far beyond congestion—fatigue is one of the most commonly reported symptoms and is often mistaken for depression or chronic fatigue syndrome.
Chronic sinusitis can also disrupt sleep, creating a cycle of worsening exhaustion. It may alter the sound of your voice and significantly affect confidence and quality of life. Breathing difficulties are another serious concern, and CRS can even contribute to the development of asthma. Many adults diagnosed with asthma first experience chronic sinusitis, because inflammation in the upper airway can trigger or worsen inflammation in the lungs. In many cases, treating chronic sinusitis leads to noticeable improvement or complete resolution of asthma symptoms, chronic cough, and other breathing problems.
For the treatment of chronic sinusitis, Modena Allergy & Asthma – Eastlake takes a personalized, science-based approach that considers the many factors contributing to your symptoms. Chronic sinusitis is a highly heterogeneous condition, meaning its underlying causes can vary significantly from one person to another. Today, the term “chronic sinusitis” is considered an umbrella diagnosis encompassing multiple subtypes of inflammation and disease. The first step in effective treatment is understanding the specific type of inflammation you have.
One of the most common patterns is known as Type 2 inflammation, the same pathway involved in allergies, eczema, atopic dermatitis, and asthma. This type of inflammation can be identified through a combination of clinical history, specialized inflammatory breathing tests, laboratory work, and, when necessary, more advanced technologies, such as genetic or molecular markers.
The exciting news is that monoclonal antibody therapies are now available to directly target Type 2 inflammation. And this is only the beginning—new biologic therapies are emerging every year to address additional inflammatory subtypes within the airways, opening the door to more precise and effective care.
At Modena Allergy & Asthma – Eastlake, we combine our deep understanding of sinus disease and immunology with advanced diagnostics, imaging, and biomarker testing to classify your inflammatory “type.” This classification enables us to create a personalized treatment plan that aligns with your specific symptoms, preferences, and long-term objectives. Our team provides comprehensive care for patients with chronic sinusitis of all ages, from children to adults, ensuring personalized treatment tailored to every stage of life.

If you struggle with chronic sinusitis, have undergone repeated nasal surgeries, or experience asthma or a chronic cough that worsens with constant drainage, it may be time to seek care at Modena Allergy & Asthma – Eastlake. Even if you’ve tried multiple treatments without lasting improvement, or want real relief from persistent symptoms, our team is here to help.
Dr. Modena and his expert staff are dedicated to restoring your comfort, improving your breathing, and helping you reclaim the quality of life you deserve. Schedule a consultation today and take the first step toward feeling better.
For patients with chronic sinusitis in Eastlake, the Modena Allergy & Asthma – Eastlake team typically performs or recommends allergy skin testing, lab work, CT imaging, and, when appropriate, nasal endoscopy. If you have had any of these procedures completed elsewhere, we encourage you to grant us access to your previous records so we can streamline your evaluation and provide timely recommendations.
Your first visit will focus on gathering a detailed medical history and determining which additional tests may be needed. During your follow-up appointment, our team will review your results with you and outline a clear, personalized treatment plan tailored to your symptoms and goals.

We'll tailor your chronic sinus treatment with personalized monoclonal antibody therapy and other effective methods. Our comprehensive approach includes allergy skin testing, CT imaging, nasal endoscopy, and immunotherapy to provide lasting relief for sinusitis.
Chronic sinusitis is a common condition throughout the United States, but the treatments available today are evolving rapidly and becoming increasingly effective every year. Our understanding of this condition has advanced dramatically over the past decade, leading to more precise diagnostics and far more targeted therapies. Allergy and Immunology specialists—experts in identifying and modifying immune-driven inflammation—play a central role in determining the specific type of sinus inflammation you have and recommending the most appropriate treatments. We also collaborate closely with ENT specialists to ensure you receive comprehensive, coordinated care.
Dr. Brian Modena has dedicated his career to advancing relief for patients with allergies, asthma, and chronic sinus disease. If you’re ready for clearer answers and better long-term control, schedule your consultation at Modena Allergy & Asthma – Eastlake today.
Untreated chronic sinusitis can lead to serious complications, as the infection may spread to vital areas, including the bones, spinal fluid, or even the brain. This increases the risk of developing life-threatening conditions such as meningitis and brain abscesses, which require urgent surgical intervention.