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Relieve chronic congestion, improve breathing, and prevent recurrence of nasal polyps with advanced treatment options.
At Modena Allergy & Asthma, our expert team of allergists and immunologists leads the way in the diagnosis and treatment of nasal polyps and chronic sinus disease. We use advanced, precision-based approaches—such as microbiome and genetic analysis, inflammatory biomarker evaluation, and AI-assisted case review—to uncover the underlying causes of your condition and guide targeted care.
These innovative tools allow us to craft highly personalized treatment plans and identify the most effective therapies for each individual. For patients seeking the latest advancements, we also offer access to cutting-edge clinical trials. If nasal polyps are interfering with your quality of life, know that lasting relief is possible—with the right care, it starts here.
Nasal polyps are soft, non-cancerous growths that form in the sinuses and can extend into the nasal passages. While painless, they result from chronic inflammation and often lead to symptoms like nasal congestion, facial pressure, sinus infections, and a diminished sense of taste or smell.
For many patients with chronic rhinosinusitis, nasal polyps contribute to a cycle of ongoing discomfort, marked by persistent congestion, postnasal drip, recurrent infections, and even debilitating fatigue. These growths are frequently linked to other conditions, including asthma and NSAID-exacerbated respiratory disease (NERD), a disorder in which patients react adversely to common pain relievers such as aspirin and ibuprofen. Understanding and treating these underlying connections is key to achieving lasting relief.
Nasal polyp treatment has advanced dramatically in recent years, offering new hope for long-term relief. In the past, options were limited. Surgery (polypectomy) provided short-term improvement, but polyps often returned—sometimes in as many as 60% of cases. Oral and nasal steroids could manage symptoms, but long-term use came with serious side effects, including weight gain, increased infection risk, diabetes, and bone loss.
Today, targeted biologic therapies offer a game-changing, non-surgical alternative by addressing the underlying cause: chronic inflammation. These advanced treatments help reduce polyp size, relieve congestion and sinus pressure, restore the senses of smell and taste, and significantly reduce the need for steroids or repeat surgeries. At Modena Allergy & Asthma, we guide each patient toward the most effective approach, including cutting-edge monoclonal antibody therapies designed to deliver sustainable, long-term relief without invasive procedures.
Modena Allergy & Asthma is actively enrolling participants for three clinical trials focused on advancing treatment options for chronic rhinosinusitis with nasal polyps.
Those who qualify may receive:
If you're living with nasal polyps and exploring new treatment options, our current clinical trials may be an opportunity to find relief while contributing to future breakthroughs.
A Phase 3 clinical trial assessing the safety and effectiveness of an investigational treatment for nasal polyps. The study includes both active treatment and placebo groups.
A Phase 4 clinical trial evaluating the long-term outcomes of an FDA-approved treatment for nasal polyps. All participants will receive active therapy—no placebo involved.
A Phase 4 clinical trial comparing the results of two FDA-approved therapies for nasal polyps. All participants will receive active treatment—no placebo is used.
Non-surgical treatments for nasal polyps typically involve minimal to no downtime. Patients receiving biologic therapies often begin to experience symptom relief within a few weeks and report few side effects. If nasal sprays or saline rinses are part of your care plan, using them consistently is essential to maximize their effectiveness.
For patients who undergo surgery, it’s common to have mild congestion and swelling in the days following the procedure. To support healing, your provider may recommend rest, saline rinses, and avoiding strenuous activity. Scheduled follow-up visits play an important role in tracking recovery and ensuring the best long-term results.
Nasal polyps form as a result of ongoing inflammation in the nasal passages and sinus cavities. They are commonly associated with conditions like allergies, asthma, recurrent sinus infections, and sensitivity to NSAIDs—medications such as aspirin or ibuprofen. In some cases, genetic factors may also contribute to a person’s likelihood of developing nasal polyps.
Nasal polyps won’t shrink or go away on their own. Without treatment, they often continue to grow, causing increased congestion, frequent sinus infections, and a reduced sense of smell. However, with the right medical therapy, it's possible to significantly reduce their size and relieve symptoms—often without the need for surgery.
The most effective treatment for nasal polyps depends on the severity of your symptoms and underlying conditions. For many patients, biologic therapies offer a modern, non-surgical solution that reduces polyp size and lowers the risk of regrowth. Nasal steroid sprays are often used to control inflammation and manage milder symptoms. In more advanced or persistent cases, surgery may be recommended to remove the polyps and restore proper airflow.
Common signs of nasal polyps include ongoing nasal congestion, facial pressure, postnasal drip, and a diminished sense of smell or taste. Unlike symptoms caused by a cold or seasonal allergies, these issues often persist for weeks or even months. At Modena Allergy & Asthma, our specialists can diagnose nasal polyps through a detailed exam and, if needed, imaging studies to confirm the diagnosis and guide treatment.
Nasal polyps can recur, particularly following surgical removal. However, newer anti-inflammatory treatments, including biologic therapies, have made it possible to reduce the risk of regrowth and maintain long-term symptom control. The key to preventing recurrence lies in a personalized treatment plan tailored to each patient’s needs and underlying causes.
Home remedies like saline rinses, steam inhalation, and allergen avoidance may offer temporary symptom relief, but they won’t shrink or eliminate nasal polyps. For long-term improvement, medical treatment is usually necessary to address the underlying inflammation and prevent the condition from worsening.
