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At Modena Health, we provide advanced testing and treatment options for eosinophilic diseases.
When the term allergy comes to mind, it's common to link it with symptoms like sneezing, itchy nose, and eyes. However, allergists today are skilled in diagnosing and managing immune system disorders beyond these symptoms. At our office close to Solana Beach, Inflammatory/Eosinophilic Diseases are among the most prevalent immune conditions we address. These include hypereosinophilic syndrome (HES), severe eosinophilic asthma, eosinophilic pneumonia, eosinophilic skin rashes, eosinophilic granulomatosis, polyangiitis (EGPA)...
and eosinophilic gastrointestinal disease (EGID) [which encompasses eosinophilic gastritis (EoG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC)]. Dr. Brian Modena and his team excel in identifying and treating both eosinophilic and other inflammatory diseases. If you've been diagnosed or suspect you might have an eosinophilic immune disorder or wish to learn more about these conditions and our treatment options, reach out to the allergy specialists at Modena Health today.
Eosinophils are a type of white blood cell that help the body fight certain infections. In the past, they played a key role in defending against parasites in the gut and lungs. Today, in places like the U.S. where these infections are uncommon, low eosinophil levels rarely cause problems. Trouble occurs when eosinophils multiply in excess and enter tissues, causing inflammation and damage. In the lungs, this can lead to eosinophilic pneumonia or severe eosinophilic asthma. In the esophagus, it may cause difficulty swallowing or food impaction.
In the digestive tract, symptoms can include bloating, abdominal pain, and diarrhea. In the airways, eosinophils can trigger narrowing and long-term breathing problems.These eosinophil-related conditions are more common in people with asthma or chronic sinus problems such as nasal polyps. If you’ve been diagnosed with an eosinophilic disease or have ongoing sinus or lung issues, Modena Health can help identify the cause and create a targeted treatment plan.
Hypereosinophilic syndrome (HES) is a rare disorder in which the body produces too many eosinophils—a type of white blood cell. These excess cells build up in tissues and can cause serious damage.
Eosinophils help defend against parasites such as intestinal worms, but in modern settings where these infections are rare, they are more often linked to harmful inflammation. HES can contribute to conditions like eosinophilic gastrointestinal disease, asthma, nasal polyps, sinusitis, and certain chronic skin problems.
The skin, lungs, digestive tract, heart, blood vessels, and nervous system are most often affected. If left untreated, HES can become life-threatening.
Asthma, drug reactions, parasitic infections, and certain allergic conditions can all raise eosinophil levels. These “secondary” causes are treated first—such as clearing a parasitic infection—before addressing primary hypereosinophilic syndrome (HES).
If treatment is needed, options often start with steroids or Nucala® (mepolizumab) for idiopathic HES. Depending on the type and response, other medications like Glivec® (imatinib), hydroxyurea, vincristine, cyclophosphamide, benralizumab, or interferon-alpha may be used.
Dr. Modena and his team have over a decade of experience treating and researching allergic and eosinophilic disorders. Their work spans microbiome studies, genetics, inflammatory biomarkers, and the use of AI to refine treatments. At Modena Allergy & Asthma near Solana Beach, we lead research to improve understanding and care for eosinophilic conditions, including offering clinical trial opportunities for patients with HES.If you wish to explore participation in this clinical trial further, please click the contact us button below.
Monoclonal antibody therapies are lab-engineered antibodies designed to target specific parts of the immune system that drive inflammation. While our bodies naturally produce antibodies to combat infections, these specialized versions specifically target reducing overactive immune responses associated with certain diseases. For people with inflammatory or eosinophilic conditions, these treatments can lower eosinophil levels and improve symptoms, often with fewer side effects than long-term steroid use.
Different monoclonal antibodies are approved for conditions such as eczema, chronic sinusitis, nasal polyps, and asthma.At Modena Health near Solana Beach, we use testing to identify the therapy best suited to your needs, so treatment is precise, effective, and personalized.
Experiencing persistent sinus issues, asthma, eczema, or gastrointestinal problems? Consulting an allergy specialist can make a difference. At Modena Health near Solana Beach, Dr. Brian Modena and his team provide personalized care for inflammatory and eosinophilic conditions.
Comprehensive evaluations and specialized testing help uncover rare diagnoses often missed elsewhere. Dr. Modena's active involvement in genetic research ensures precise solutions, potentially incorporating advanced gene sequencing techniques for effective treatment.
Before your first visit, providing any past medical notes, labs, or imaging can greatly improve the conversation with your doctor and speed up the evaluation.
You'll receive a Medical Release Form via email. Please complete it so we can gather your records from other doctors. Modena Health may also order specialized labs, imaging, and allergy skin testing for a thorough assessment. At a follow-up in 1-2 weeks, our specialists will review all results with you to create a clear action plan.
Managing inflammatory and eosinophilic diseases requires a personalized approach, as recovery varies significantly for each individual. While some experience quick relief, treatment plans often focus on reducing flare-ups over time to achieve lasting remission. If you're dealing with an eosinophilic condition, consulting with our allergy specialists in Solana Beach can help tailor the right treatment options for you. Our team is dedicated to providing compassionate care and expert guidance on your journey to better health.
Antibody therapies offer a promising approach to treating inflammatory and eosinophilic diseases by specifically reducing eosinophils in the body. Compared to traditional steroid treatments, these therapies are generally safer and more effective. At our practice, we've seen impressive results with these targeted options. While individual responses can vary, we're committed to helping you find relief and improve your quality of life.
Dr. Brian Modena and his dedicated team at Modena Health specialize in assessing and managing eosinophilic diseases and other inflammatory conditions in Solana Beach. With a focus on personalized care, they aim to provide effective solutions tailored to your needs. Arrange your consultation today to explore how their expertise can support your health journey.
Antibody therapies show promise for eosinophilic conditions, offering a safer and often more effective alternative to steroids. While their potential for a permanent cure or long-term remission is still uncertain, these treatments can significantly ease symptoms and prevent lasting damage with timely intervention.
Antihistamines are great for tackling those pesky itchy noses or skin reactions, but they're not the go-to solution for more complex conditions like inflammatory or eosinophilic disorders. These require targeted treatments that address the underlying directly, often involving a different set of medications tailored to reduce inflammation and manage symptoms effectively. Always consult with a healthcare provider to explore the best options for your specific needs.
