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Modena Allergy & Asthma in Long Beach offers expert diagnosis and treatment for eosinophilic diseases, including asthma, HES, and GI disorders.
Allergies are more than just sneezing or itchy eyes. At Modena Allergy & Asthma, we specialize in complex immune conditions, including eosinophilic diseases that often go undiagnosed or mismanaged. These inflammatory disorders can impact the lungs, skin, and gastrointestinal tract, often leading to chronic symptoms and reduced quality of life.
Using advanced diagnostics, personalized treatment plans, and the latest biologic therapies, we’re committed to helping you take control of your symptoms and restore your quality of life. Whether you’ve received a recent diagnosis or are still searching for answers, our Long Beach specialists are here to guide you every step of the way.
If you’re dealing with unresolved or difficult-to-treat conditions like chronic sinusitis, asthma, eczema, or gastrointestinal symptoms, you may be a candidate for inflammatory disease testing. These conditions are sometimes linked to eosinophilic or immune system disorders that require a specialized approach.
At Modena Allergy & Asthma, we offer in-depth evaluations that go beyond standard care. Our expert team is known for uncovering overlooked diagnoses using advanced testing, detailed health histories, and clinical insight. We also utilize cutting-edge tools—like genomic profiling and targeted gene sequencing—to help identify root causes and guide precise treatment.
When other answers fall short, we’re here to help you move forward with clarity, confidence, and customized care.
Our expert team diagnoses and treats a wide range of eosinophilic conditions, including:
Eosinophils are a type of white blood cell that help the body respond to infections and support tissue repair. While their original role was defending against parasites—especially in the gut and lungs—these infections are now rare in developed countries. As a result, low eosinophil levels typically have little impact on overall health.
However, when eosinophils become overactive or multiply excessively, they can trigger inflammation and damage tissues. This group of immune-related conditions is known as eosinophilic diseases.
Hypereosinophilic Syndrome (HES) is a rare but serious condition in which the body produces too many eosinophils. These cells then build up in the bloodstream and tissues, causing inflammation and long-term damage to organs such as the heart, lungs, skin, and gastrointestinal tract.
Early diagnosis and targeted treatment are essential to prevent complications and manage symptoms effectively.
Eosinophilic asthma is a severe form of asthma driven by high levels of eosinophils in the lungs. This type of asthma is often more difficult to control with standard inhalers and may cause persistent symptoms such as coughing, wheezing, shortness of breath, and chest tightness.
Unlike typical asthma, eosinophilic asthma is linked to underlying inflammation rather than external triggers like allergens. Advanced treatments—such as biologic therapies—can help reduce eosinophil levels, decrease flare-ups, and improve breathing.
Eosinophilic Granulomatosis with Polyangiitis, formerly known as Churg-Strauss Syndrome, is a rare inflammatory condition that affects small- to medium-sized blood vessels. It’s characterized by asthma, high eosinophil levels, and organ damage—most often impacting the lungs, sinuses, skin, and nerves.
Because EGPA is a systemic vasculitis (a condition that causes inflammation of the blood vessels), it requires early diagnosis and ongoing care. At Modena Allergy & Asthma, we provide expert, multidisciplinary management to reduce inflammation and protect long-term organ function.
Eosinophilic gastrointestinal diseases (EGIDs) are a group of chronic disorders where eosinophils build up in different parts of the digestive tract, causing inflammation and damage. Common types include:
These conditions are often linked to food allergies or immune dysfunction and may be diagnosed through endoscopy and tissue biopsy. Treatments can include dietary modifications, biologic therapies, and targeted medication to reduce inflammation and improve quality of life.
Before your first appointment, we request access to any relevant medical records—such as past labs, imaging, or physician notes. Reviewing this information in advance allows our team to better understand your history, ask the right questions, and potentially uncover a more accurate diagnosis.
To get started, you’ll receive a Medical Release Form by email. Once you sign it, we’ll take care of the rest—contacting your previous provider and securing your records on your behalf.
During your visit, your allergist may recommend advanced diagnostics, including specialized blood work, allergy skin testing, or imaging studies. A follow-up appointment is typically scheduled within 1–2 weeks, where your doctor will walk through your results in detail and create a personalized treatment plan designed to get you the relief you deserve.
Eosinophilic conditions often arise from other underlying issues—such as asthma, allergic reactions, parasitic infections, or medication sensitivities. These are known as secondary causes. That’s why the first step in treatment is identifying and addressing any potential root cause, like an undiagnosed infection or drug reaction.
If no secondary cause is found—or if symptoms persist—your provider may determine that treatment is necessary. In these cases, we offer a range of precision therapies based on your diagnosis and how your body responds.
Common treatment options include:
Every treatment plan at Modena Allergy & Asthma is personalized. It is designed to reduce eosinophil levels and improve your day-to-day comfort and long-term health.
If you have high eosinophil counts or unexplained sinus, lung, or gastrointestinal symptoms, our experts are here to help.
Monoclonal antibody (mAb) therapy represents one of the most significant medical breakthroughs in the treatment of chronic inflammatory conditions. While your body naturally produces antibodies to fight infection, scientists have developed lab-engineered antibodies that target specific pathways in the immune system—making treatment more precise, powerful, and safer than traditional therapies like steroids.
For patients with eosinophilic diseases, monoclonal antibodies are designed to reduce eosinophil levels and prevent inflammation at the source. These therapies have become a game-changer in managing conditions like:
Unlike steroids, which often come with long-term side effects, monoclonal antibodies are targeted and generally well-tolerated—making them ideal for long-term care.
At Modena Allergy & Asthma, we match the right biologic to your diagnosis based on in-depth testing and immune profiling. Our goal is to help you take control of your symptoms with safe, effective solutions tailored to your needs—so you can breathe easier, live better, and feel like yourself again.
Recovering from an eosinophilic condition is not one-size-fits-all—it’s a deeply individualized journey. Some patients respond quickly to treatment, while others may need ongoing care to manage symptoms and prevent flare-ups. Our goal is to help every patient move toward long-term remission, reduced inflammation, and improved quality of life. With expert guidance and a personalized treatment plan, you can gain better control over your condition and feel confident in your care every step of the way.
Monoclonal antibody therapies are transforming care for eosinophilic and inflammatory conditions. By precisely targeting and lowering eosinophil levels, these treatments offer safer, more effective relief than traditional steroids. At Modena Allergy & Asthma, we've seen firsthand how these advanced therapies can reduce symptoms, prevent flare-ups, and restore day-to-day comfort. While results vary by individual, many patients experience fewer complications, better disease control, and a meaningful improvement in overall quality of life.
Modena Allergy & Asthma is proud to lead the way in innovative care for eosinophilic diseases. With over a decade of experience in treating and researching conditions like hypereosinophilic syndrome (HES), our team integrates the latest science in microbiome analysis, genetics, biomarker discovery, and machine learning to deliver highly personalized treatment strategies.
We are currently enrolling qualified patients in a groundbreaking clinical trial for HES. This is a unique opportunity to access investigational treatments while contributing to the future of eosinophilic disease care. Join us in shaping the next generation of therapy—and take a step toward lasting relief.
The frequency of treatment varies depending on the specific therapy, but generally falls between every 2 to 8 weeks. This schedule allows for proper monitoring and adjustments as needed to ensure the best outcomes for patients.
In some cases, adjusting diet, trying alternative remedies, or altering habits can improve the effectiveness of antibody therapy for enhanced results. This holistic strategy aims to aid healing and optimize treatment success. By integrating these complementary methods, patients may notice better outcomes and enhanced well-being during antibody therapy.
